You should be able to access it via normal methods of fetching data from servers (either through NSURLConnection, libraries (such as TouchXML), etc).
The only thing you need concern yourself about is the CA (certificate authority) who issued the SSL/TLS certificate. The iPhone ships with a list of "trusted" CA's - if you self-sign or use a CA which is not trusted by the iPhone OS (iOS), the connection will
FAIL.
You can find out what CA's are trusted here:
iPhone OS 3.x: List of available trusted root certificates